Source:http://linkedlifedata.com/resource/pubmed/id/15852202
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2005-4-26
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pubmed:abstractText |
The possible association of estrogen (E) with or without progestin (P) and breast cancer has been addressed in many studies for several decades. The recent reported prospective double-blind Women's Health Initiative (WHI) study suggests that E + P increases the risk of breast cancer if a woman is an average of 63 years old when she begins replacement therapy. One third of the patients in this study were 70 to 79 years of age when E + P was begun--obviously several decades past menopausal. Retrospective and observational studies suggest protection or no increased risk. The WHI-E only study actually notes a 23% reduction in breast cancer compared with the placebo. It would appear from a review of the literature that if there is an increased risk for breast cancer with E or E + P, it is minimal.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1526-8004
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
167-71
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15852202-Aged,
pubmed-meshheading:15852202-Breast Neoplasms,
pubmed-meshheading:15852202-Estrogen Replacement Therapy,
pubmed-meshheading:15852202-Estrogens,
pubmed-meshheading:15852202-Female,
pubmed-meshheading:15852202-Humans,
pubmed-meshheading:15852202-Middle Aged,
pubmed-meshheading:15852202-Progestins,
pubmed-meshheading:15852202-Randomized Controlled Trials as Topic
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pubmed:year |
2005
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pubmed:articleTitle |
Breast cancer: the role of hormone therapy.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, University Midlife Women's Health, Medical University of South Carolina, 1280 Johnnie Dodds Boulevard, Mt. Pleasant, SC 29464, USA. creasman@musc.edu
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pubmed:publicationType |
Journal Article,
Review
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