Linked Life Data

15849966

Source:http://linkedlifedata.com/resource/pubmed/id/15849966

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-4-26
pubmed:abstractText
A strain from Aedes aegypti (L) collected in the municipality of Santiago de Cuba with low levels of resistance to malathion (1.79x) was subjected to selection pressure aimed at evaluating the evolution of the resistance to this organophosphate and its usefulness for control. After 5 generations of selection (SAN-F5) with malathion, it was not possible to increase the resistance and it was obtained a value of resistance factor (FR50) of 2.22x. None or little cross resistance to the following organophosphate insecticides was observed: fenthion, temephos and fenitrotion; however, it was found an elevated cross resistance to deltamethrin pyrethroid, with a value of 287.5x in the third generation of selection. It was also observed cross resistance to other pyrethroids (lambda-cyhalothrin, cypermethrin and ciflutrine). The mechansim of elevated esterases did not generate resistance to pyrethroids, which was corroborated through inhibition gel studies and through the calculation of the frequency in microtitering plaques. Nevertheless, there was an increase in the frequency of the glutathione-s-transferase mechanism from 0.049 in Santiago de Cuba to 0.42 in SAN-F5, which may be associated with the resistance to pyrethroids. The cross resistance to pyrethroids, mainly to deltamethrin, resulting from the selection with malathion may limit the use of these insecticides in the control unless a good strategy for their use is laid down.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0375-0760
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
105-11
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:articleTitle
[Cross resistance to pyrethroids in Aedes aegypti from Cuba induced by the selection with organophosphate malathion].
pubmed:affiliation
Instituto de Medicina Tropical "Pedro Kourí", Ciudad de La Habana, Cuba. ciipk@ipk.sld.cu
pubmed:publicationType
Journal Article, English Abstract