Linked Life Data

15845907

Source:http://linkedlifedata.com/resource/pubmed/id/15845907

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2005-6-27
pubmed:abstractText
The interaction of advanced glycation end products (AGEs) with their main receptor RAGE in endothelial cells induces intracellular generation of reactive oxygen species (ROS) and the expression of vascular cell adhesion molecule (VCAM)-1. We investigated the role of distinct sources of ROS, including the mitochondrial electron transport chain, NAD(P)H oxidase, xanthine oxidase, and arachidonic acid metabolism, in AGE-induced VCAM-1 expression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Arachidonic Acid, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Glycosylation End Products, Advanced, http://linkedlifedata.com/resource/pubmed/chemical/NADPH Oxidase, http://linkedlifedata.com/resource/pubmed/chemical/Reactive Oxygen Species, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic, http://linkedlifedata.com/resource/pubmed/chemical/Superoxide Dismutase, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor RelA, http://linkedlifedata.com/resource/pubmed/chemical/Vascular Cell Adhesion Molecule-1, http://linkedlifedata.com/resource/pubmed/chemical/Xanthine Oxidase, http://linkedlifedata.com/resource/pubmed/chemical/advanced glycosylation end-product...
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1524-4636
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1401-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:15845907-Arachidonic Acid, pubmed-meshheading:15845907-Atherosclerosis, pubmed-meshheading:15845907-Cell Nucleus, pubmed-meshheading:15845907-Cells, Cultured, pubmed-meshheading:15845907-Cytoplasm, pubmed-meshheading:15845907-Electron Transport, pubmed-meshheading:15845907-Endothelium, Vascular, pubmed-meshheading:15845907-Enzyme Inhibitors, pubmed-meshheading:15845907-Glycosylation End Products, Advanced, pubmed-meshheading:15845907-Humans, pubmed-meshheading:15845907-Mitochondria, pubmed-meshheading:15845907-NADPH Oxidase, pubmed-meshheading:15845907-Reactive Oxygen Species, pubmed-meshheading:15845907-Receptors, Immunologic, pubmed-meshheading:15845907-Signal Transduction, pubmed-meshheading:15845907-Superoxide Dismutase, pubmed-meshheading:15845907-Transcription Factor RelA, pubmed-meshheading:15845907-Umbilical Veins, pubmed-meshheading:15845907-Vascular Cell Adhesion Molecule-1, pubmed-meshheading:15845907-Xanthine Oxidase
pubmed:year
2005
pubmed:articleTitle
At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products.
pubmed:affiliation
C.N.R. Institutes of Clinical Physiology, Pisa, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't