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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-6-18
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pubmed:abstractText |
The effects of noise exposure were studied in fifty-nine 4- to 5-week-old albino Hartley guinea pigs with normal hearing (body weight 250-300 g). The following experiments and results were carried out: exposure to 350 Hz pure tones at 115 dB for 40 h and exposure to 350 Hz tones at 120 dB for 64 h. In order to investigate the effects of low-frequency tone exposures on the hearing of the guinea pigs, cochlear microphonics (CM), whole nerve action potentials (AP) and endocochlear potentials (EP) were measured. With a high-sound pressure, a decrease was observed in the CM maximum output voltage in the test frequencies of 2, 4 and 6 kHz while the CM threshold (pseudothreshold) of 6 kHz was elevated. Output voltage of the N1 potential of the AP using a 7-kHz tone burst decreased while the threshold of the N1 potential was elevated. An extension of latency and a decrease in the absolute value of the negative potential in EP were also observed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0301-1569
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
10-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1584586-Acoustics,
pubmed-meshheading:1584586-Action Potentials,
pubmed-meshheading:1584586-Animals,
pubmed-meshheading:1584586-Cochlea,
pubmed-meshheading:1584586-Cochlear Microphonic Potentials,
pubmed-meshheading:1584586-Cochlear Nerve,
pubmed-meshheading:1584586-Guinea Pigs,
pubmed-meshheading:1584586-Hearing,
pubmed-meshheading:1584586-Noise,
pubmed-meshheading:1584586-Reaction Time
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pubmed:year |
1992
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pubmed:articleTitle |
Study of the effect of 350-Hz tone exposure on electrophysiological function of the inner ear of guinea pigs.
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pubmed:affiliation |
Department of Hygiene, Asahikawa Medical College, Hokkaido, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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