| pubmed-article:15845499 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15845499 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:15845499 | lifeskim:mentions | umls-concept:C0001779 | lld:lifeskim |
| pubmed-article:15845499 | lifeskim:mentions | umls-concept:C0032594 | lld:lifeskim |
| pubmed-article:15845499 | lifeskim:mentions | umls-concept:C0700144 | lld:lifeskim |
| pubmed-article:15845499 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:15845499 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:15845499 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:15845499 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:15845499 | lifeskim:mentions | umls-concept:C0439234 | lld:lifeskim |
| pubmed-article:15845499 | lifeskim:mentions | umls-concept:C0205473 | lld:lifeskim |
| pubmed-article:15845499 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:15845499 | pubmed:dateCreated | 2005-4-22 | lld:pubmed |
| pubmed-article:15845499 | pubmed:abstractText | An immunization campaign with meningococcal ACYW135 polysaccharide vaccine was conducted in 2003 by the Saudi Arabian Ministry of Health and included a study to evaluate the immune responses in children under 5 years of age in the Al Qassim region of Saudi Arabia. Children who were >/=24 months old were given one dose of tetravalent polysaccharide vaccine, while younger children were given two doses with an interval of 2 to 3 months. Blood samples were collected prevaccination and 1 month after the second dose for children younger than 24 months old and 1 month after the single dose for older children. Serogroup-specific antibody responses were determined by serum bactericidal antibody (SBA) assays and a tetraplex immunoglobulin G (IgG) bead assay. Significant increases in the proportions of individuals who were >/=24 months old with SBA titers of >/=8 were observed pre- to postvaccination for all serogroups. Age-dependent increases in the percentage of individuals with SBA titers of >/=8 1 month postvaccination were observed for each serogroup. Age-dependent increases in postvaccination IgG levels were observed for serogroup A (menA), serogroup W135 (menW), and serogroup Y (menY) but not for serogroup C (menC). Two doses of tetravalent polysaccharide vaccine in individuals who were </=18 months old were poorly immunogenic for menC, menW, and menY. However, for menA, 42% of the children who were 18 months old were putatively protected with SBA titers of >/=8. A high percentage of subjects who were >/=2 years of age were putatively protected for menA; a similar level was observed for menY for children who were 4 years of age but not for younger children. However, for menC and menW poor levels of putative protection were still evident at 4 years of age. | lld:pubmed |
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| pubmed-article:15845499 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15845499 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15845499 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15845499 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15845499 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:15845499 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15845499 | pubmed:month | May | lld:pubmed |
| pubmed-article:15845499 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:15845499 | pubmed:author | pubmed-author:KhalilMM | lld:pubmed |
| pubmed-article:15845499 | pubmed:author | pubmed-author:LaiDD | lld:pubmed |
| pubmed-article:15845499 | pubmed:author | pubmed-author:AndrewsNN | lld:pubmed |
| pubmed-article:15845499 | pubmed:author | pubmed-author:BorrowRR | lld:pubmed |
| pubmed-article:15845499 | pubmed:author | pubmed-author:BalmerPP | lld:pubmed |
| pubmed-article:15845499 | pubmed:author | pubmed-author:Al-MazrouYY | lld:pubmed |
| pubmed-article:15845499 | pubmed:author | pubmed-author:Al-JeffriMM | lld:pubmed |
| pubmed-article:15845499 | pubmed:author | pubmed-author:BramwellJJ | lld:pubmed |
| pubmed-article:15845499 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15845499 | pubmed:volume | 73 | lld:pubmed |
| pubmed-article:15845499 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15845499 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15845499 | pubmed:pagination | 2932-9 | lld:pubmed |
| pubmed-article:15845499 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:15845499 | pubmed:meshHeading | pubmed-meshheading:15845499... | lld:pubmed |
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| pubmed-article:15845499 | pubmed:meshHeading | pubmed-meshheading:15845499... | lld:pubmed |
| pubmed-article:15845499 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15845499 | pubmed:articleTitle | Serologic responses to ACYW135 polysaccharide meningococcal vaccine in Saudi children under 5 years of age. | lld:pubmed |
| pubmed-article:15845499 | pubmed:affiliation | Meningococcal Reference Unit, HPA North West Laboratory, Manchester Royal Infirmary, Manchester, United Kingdom. | lld:pubmed |
| pubmed-article:15845499 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15845499 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:15845499 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:15845499 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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