15842554

Source:http://linkedlifedata.com/resource/pubmed/id/15842554

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008287, umls-concept:C0032529, umls-concept:C0743223, umls-concept:C1332828, umls-concept:C1332829, umls-concept:C1533691
pubmed:issue	5
pubmed:dateCreated	2005-4-21
pubmed:abstractText	We evaluated the involvement of cytochrome P450 (CYP) isoforms 2C9 and 2C19 in chlorpropamide 2-hydroxylation in vitro and in chlorpropamide disposition in vivo.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7503323
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases, http://linkedlifedata.com/resource/pubmed/chemical/CYP2C19 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CYP2C9 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Chlorpropamide, http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Mixed Function Oxygenases
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	0306-5251
pubmed:author	pubmed-author:ChaIn-JuneIJ, pubmed-author:KimKyoung-AhKA, pubmed-author:KimMin-JungMJ, pubmed-author:LeeChung HanCH, pubmed-author:LimYoung-ChaeYC, pubmed-author:LiuKwang-HyeonKH, pubmed-author:ShinDong-HoonDH, pubmed-author:ShinJae-GookJG, pubmed-author:ShonJi-HongJH, pubmed-author:YoonYoung-RanYR
pubmed:issnType	Print
pubmed:volume	59
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	552-63
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:15842554-Administration, Oral, pubmed-meshheading:15842554-Adult, pubmed-meshheading:15842554-Aryl Hydrocarbon Hydroxylases, pubmed-meshheading:15842554-Chlorpropamide, pubmed-meshheading:15842554-Female, pubmed-meshheading:15842554-Humans, pubmed-meshheading:15842554-Hydroxylation, pubmed-meshheading:15842554-Hypoglycemic Agents, pubmed-meshheading:15842554-Liver, pubmed-meshheading:15842554-Male, pubmed-meshheading:15842554-Microsomes, pubmed-meshheading:15842554-Mixed Function Oxygenases, pubmed-meshheading:15842554-Polymorphism, Genetic
pubmed:year	2005
pubmed:articleTitle	Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism.
pubmed:affiliation	Department of Pharmacology and PharmacoGenomics Research Centre, Inje University College of Medicine and Clinical Pharmacology Centre, Busan Paik Hospital, Busan 641-735, Korea.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't