Source:http://linkedlifedata.com/resource/pubmed/id/15838265
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2005-4-19
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pubmed:abstractText |
The use of reporter genes such as beta-galactosidase and green fluorescent protein is a powerful molecular tool for the visualization of in-vivo gene expression. In this paper, we describe the generation of mice that possess a beta-galactosidase reporter gene introduced into the endothelin-B receptor locus by homologous recombination in embryonic stem cells. These mice express beta- galactosidase wherever endothelin-B is expressed and therefore provide a precise in-vivo localization profile of endothelin-B expression.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1533-4023
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
44 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S144-6
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pubmed:meshHeading |
pubmed-meshheading:15838265-Animals,
pubmed-meshheading:15838265-Embryonic Stem Cells,
pubmed-meshheading:15838265-Genes, Reporter,
pubmed-meshheading:15838265-Genetic Vectors,
pubmed-meshheading:15838265-Lac Operon,
pubmed-meshheading:15838265-Lung,
pubmed-meshheading:15838265-Mice,
pubmed-meshheading:15838265-Mice, Transgenic,
pubmed-meshheading:15838265-Receptor, Endothelin B,
pubmed-meshheading:15838265-Recombination, Genetic,
pubmed-meshheading:15838265-beta-Galactosidase
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pubmed:year |
2004
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pubmed:articleTitle |
Localization of the endothelin-B receptor using a transgenic approach.
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pubmed:affiliation |
Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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