Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-4-18
pubmed:abstractText
We have generalized the derivation of genetic-interaction networks from quantitative phenotype data. Familiar and unfamiliar modes of genetic interaction were identified and defined. A network was derived from agar-invasion phenotypes of mutant yeast. Mutations showed specific modes of genetic interaction with specific biological processes. Mutations formed cliques of significant mutual information in their large-scale patterns of genetic interaction. These local and global interaction patterns reflect the effects of gene perturbations on biological processes and pathways.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-10090725, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-10398601, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-10436161, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-10514571, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-10802651, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-11099033, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-11104818, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-11152942, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-11232561, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-11743205, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-12073323, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-12677061, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-12690189, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-1365397, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-14597658, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-14764870, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-14992718, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-14993204, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-15016375, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-1547504, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-15485347, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-15592468, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-8904338, http://linkedlifedata.com/resource/pubmed/commentcorrection/15833125-9744864
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1465-6914
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
R38
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Derivation of genetic interaction networks from quantitative phenotype data.
pubmed:affiliation
Institute for Systems Biology, 1441 N, 34th Street, Seattle, WA 98103, USA. bdrees@u.washington.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural