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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2005-4-14
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pubmed:abstractText |
Chromosomal translocations leading to chimeric oncoproteins are important in leukemogenesis, but how they form is unclear. We studied acute promyelocytic leukemia (APL) with the t(15;17) translocation that developed after treatment of breast or laryngeal cancer with chemotherapeutic agents that poison topoisomerase II.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1533-4406
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pubmed:author |
pubmed-author:AdèsLionelL,
pubmed-author:BlairIan AIA,
pubmed-author:CassinatBrunoB,
pubmed-author:ChomienneChristineC,
pubmed-author:CrossNicholas C PNC,
pubmed-author:FelixCarolyn ACA,
pubmed-author:FenauxPierreP,
pubmed-author:GrimwadeDavidD,
pubmed-author:Lafage-PochitaloffMarinaM,
pubmed-author:MasonAnnabelA,
pubmed-author:MistryAnita RAR,
pubmed-author:OsheroffNeilN,
pubmed-author:ParryAnneA,
pubmed-author:PeniketAndrew JAJ,
pubmed-author:ReiterAndreasA,
pubmed-author:SegalMark RMR,
pubmed-author:SolomonEllenE,
pubmed-author:WalzChristophC,
pubmed-author:WhitmarshRyan JRJ,
pubmed-author:WiemelsJoseph LJL
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pubmed:copyrightInfo |
Copyright 2005 Massachusetts Medical Society.
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
352
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1529-38
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:15829534-Antineoplastic Agents,
pubmed-meshheading:15829534-DNA, Neoplasm,
pubmed-meshheading:15829534-DNA Damage,
pubmed-meshheading:15829534-DNA Repair,
pubmed-meshheading:15829534-DNA Topoisomerases, Type II,
pubmed-meshheading:15829534-Doxorubicin,
pubmed-meshheading:15829534-Etoposide,
pubmed-meshheading:15829534-Humans,
pubmed-meshheading:15829534-Leukemia, Promyelocytic, Acute,
pubmed-meshheading:15829534-Mitoxantrone,
pubmed-meshheading:15829534-Neoplasms, Second Primary,
pubmed-meshheading:15829534-Polymerase Chain Reaction,
pubmed-meshheading:15829534-Sequence Analysis, DNA,
pubmed-meshheading:15829534-Topoisomerase II Inhibitors,
pubmed-meshheading:15829534-Translocation, Genetic
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pubmed:year |
2005
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pubmed:articleTitle |
DNA topoisomerase II in therapy-related acute promyelocytic leukemia.
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pubmed:affiliation |
Department of Medical and Molecular Genetics, Guy's, King's, and St. Thomas' School of Medicine, London.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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