15825565

Source:http://linkedlifedata.com/resource/pubmed/id/15825565

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0030705, umls-concept:C0182400, umls-concept:C0205307, umls-concept:C0242485, umls-concept:C0681850, umls-concept:C0920317, umls-concept:C1168250, umls-concept:C1282910, umls-concept:C1550501, umls-concept:C1706203, umls-concept:C2349001, umls-concept:C2697811
pubmed:issue	3
pubmed:dateCreated	2005-4-13
pubmed:abstractText	We report a meta-analysis of a series of studies in which 24-hour ambulatory pH monitoring was performed in 1) normal subjects, 2) the normal control subjects in studies of laryngopharyngeal reflux (LPR), and 3) the patients with LPR in these controlled studies. The statistical analysis utilized the fixed-effects model by Mantel-Haenszel and the random-effects mixed model. There were 16 studies from the past 12 years that fulfilled the inclusion criteria. They involved 793 subjects (264 normal and 529 with LPR). The numbers of positive pharyngeal reflux events for normal subjects and for patients with LPR differed with a p value of <.0001. There was also a significant difference in the mean percentage of acid exposure times between normal subjects and patients with LPR (p = .003). We conclude that the upper probe gives accurate and consistent information in normal subjects and patients with LPR. The numbers of reflux events and acid exposure times are most important in distinguishing normal subjects from patients with LPR. The technology and methodology of probe testing is quite reliable and is consistent on a worldwide basis.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0407300
pubmed:citationSubset	AIM
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0003-4894
pubmed:author	pubmed-author:LimHyun JHJ, pubmed-author:MeratiAlbert LAL, pubmed-author:ToohillRobert JRJ, pubmed-author:UlualpSeckin OSO
pubmed:issnType	Print
pubmed:volume	114
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	177-82
pubmed:dateRevised	2006-5-15
pubmed:meshHeading	pubmed-meshheading:15825565-Case-Control Studies, pubmed-meshheading:15825565-Gastroesophageal Reflux, pubmed-meshheading:15825565-Humans, pubmed-meshheading:15825565-Hydrogen-Ion Concentration, pubmed-meshheading:15825565-Laryngeal Diseases, pubmed-meshheading:15825565-Laryngoscopy, pubmed-meshheading:15825565-Monitoring, Ambulatory, pubmed-meshheading:15825565-Pharyngeal Diseases
pubmed:year	2005
pubmed:articleTitle	Meta-analysis of upper probe measurements in normal subjects and patients with laryngopharyngeal reflux.
pubmed:affiliation	Department of Otolaryngology and Communication Sciences and the Division of Biostatistics, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226-0099, USA.
pubmed:publicationType	Journal Article, Review, Meta-Analysis