| pubmed-article:15825320 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15825320 | lifeskim:mentions | umls-concept:C0033808 | lld:lifeskim |
| pubmed-article:15825320 | lifeskim:mentions | umls-concept:C0006976 | lld:lifeskim |
| pubmed-article:15825320 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:15825320 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:15825320 | lifeskim:mentions | umls-concept:C0053853 | lld:lifeskim |
| pubmed-article:15825320 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:15825320 | pubmed:dateCreated | 2005-4-13 | lld:pubmed |
| pubmed-article:15825320 | pubmed:abstractText | Prior investigators have reported a broad gram-negative spectrum and a marked anti-Pseudomonas activity in vitro with BL-P1654, 6-[R-alpha-(guanylureido)phenylacetamido]-penicillanic acid. An in vitro comparison of BL-P1654 to carbenicillin was performed against 84 strains of Pseudomonas and 39 strains of Enterobacteriaceae. Mean minimal inhibitory concentrations in Mueller-Hinton broth of BL-P1654 and carbenicillin were 12.5 and 100 mug/ml, respectively. Bactericidal studies with representative strains of Pseudomonas showed a consistent lack of bactericidal activity with BL-P1654. Mean bactericidal concentrations of BL-P1654 and carbenicillin were >/=200 and 100 mug/ml, respectively. The lack of bactericidal activity of BL-P1654 was further substantiated with the "killing curve" technique. Based on these data, BL-P1654 can not be considered a substitute for carbenicillin as the penicillin analogue of choice for Pseudomonas infections. | lld:pubmed |
| pubmed-article:15825320 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15825320 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15825320 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15825320 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15825320 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15825320 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15825320 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15825320 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15825320 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15825320 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15825320 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15825320 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15825320 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15825320 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:15825320 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:15825320 | pubmed:author | pubmed-author:OverturfG DGD | lld:pubmed |
| pubmed-article:15825320 | pubmed:author | pubmed-author:WilkinsJJ | lld:pubmed |
| pubmed-article:15825320 | pubmed:author | pubmed-author:ResslerRR | lld:pubmed |
| pubmed-article:15825320 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15825320 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:15825320 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15825320 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15825320 | pubmed:pagination | 643-6 | lld:pubmed |
| pubmed-article:15825320 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:15825320 | pubmed:meshHeading | pubmed-meshheading:15825320... | lld:pubmed |
| pubmed-article:15825320 | pubmed:meshHeading | pubmed-meshheading:15825320... | lld:pubmed |
| pubmed-article:15825320 | pubmed:meshHeading | pubmed-meshheading:15825320... | lld:pubmed |
| pubmed-article:15825320 | pubmed:meshHeading | pubmed-meshheading:15825320... | lld:pubmed |
| pubmed-article:15825320 | pubmed:meshHeading | pubmed-meshheading:15825320... | lld:pubmed |
| pubmed-article:15825320 | pubmed:year | 1974 | lld:pubmed |
| pubmed-article:15825320 | pubmed:articleTitle | Comparative in vitro evaluation of BL-P1654 and carbenicillin against Pseudomonas. | lld:pubmed |
| pubmed-article:15825320 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15825320 | pubmed:publicationType | Comparative Study | lld:pubmed |
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