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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2005-4-12
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pubmed:abstractText |
Inherited interleukin-1-receptor-associated kinase-4 (IRAK-4) deficiency is a recently described immunodeficiency associated with pyogenic bacterial infections and a poor inflammatory response. Shigella sonnei is generally associated with outbreaks of rectocolitis in developed countries, but systemic illnesses have occasionally been reported. An underlying primary immunodeficiency has not been found in such cases before now.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1537-6591
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1227-31
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15825022-Anti-Bacterial Agents,
pubmed-meshheading:15825022-Child,
pubmed-meshheading:15825022-Dysentery, Bacillary,
pubmed-meshheading:15825022-Female,
pubmed-meshheading:15825022-Gene Expression Regulation,
pubmed-meshheading:15825022-Humans,
pubmed-meshheading:15825022-Immunologic Deficiency Syndromes,
pubmed-meshheading:15825022-Interleukin-1 Receptor-Associated Kinases,
pubmed-meshheading:15825022-Interleukin-10,
pubmed-meshheading:15825022-Interleukin-6,
pubmed-meshheading:15825022-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:15825022-Meningitis, Bacterial,
pubmed-meshheading:15825022-Protein-Serine-Threonine Kinases,
pubmed-meshheading:15825022-Shigella sonnei,
pubmed-meshheading:15825022-Trimethoprim-Sulfamethoxazole Combination
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pubmed:year |
2005
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pubmed:articleTitle |
Shigella sonnei meningitis due to interleukin-1 receptor-associated kinase-4 deficiency: first association with a primary immune deficiency.
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pubmed:affiliation |
Department of Clinical Immunology, Nuffield Department of Medicine, John Radcliffe Hospital, Headington, Oxford, United Kingdom. helen.chapel@ndm.ox.ac.uk
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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