Linked Life Data

15824852

Source:http://linkedlifedata.com/resource/pubmed/id/15824852

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-4-12
pubmed:abstractText
To clarify the role of ghrelin in bone metabolism, we examined the effect of ghrelin in vitro and in vivo. Ghrelin and its receptor, GHS-R1a, were identified in osteoblasts, and ghrelin promoted both proliferation and differentiation. Furthermore, ghrelin increased BMD in rats. Our results show that ghrelin directly affects bone formation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Alkaline Phosphatase, http://linkedlifedata.com/resource/pubmed/chemical/Calcium, http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type I, http://linkedlifedata.com/resource/pubmed/chemical/Core Binding Factor Alpha 1 Subunit, http://linkedlifedata.com/resource/pubmed/chemical/Culture Media, Serum-Free, http://linkedlifedata.com/resource/pubmed/chemical/DNA, http://linkedlifedata.com/resource/pubmed/chemical/Ghrelin, http://linkedlifedata.com/resource/pubmed/chemical/Leptin, http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Osteocalcin, http://linkedlifedata.com/resource/pubmed/chemical/Peptide Hormones, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, G-Protein-Coupled, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Ghrelin, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors, http://linkedlifedata.com/resource/pubmed/chemical/collagen type I, alpha 1 chain
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0884-0431
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
790-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:15824852-Adipocytes, pubmed-meshheading:15824852-Alkaline Phosphatase, pubmed-meshheading:15824852-Animals, pubmed-meshheading:15824852-Bone Density, pubmed-meshheading:15824852-Bone Development, pubmed-meshheading:15824852-Bone and Bones, pubmed-meshheading:15824852-Calcium, pubmed-meshheading:15824852-Cell Differentiation, pubmed-meshheading:15824852-Cell Proliferation, pubmed-meshheading:15824852-Cells, Cultured, pubmed-meshheading:15824852-Collagen Type I, pubmed-meshheading:15824852-Core Binding Factor Alpha 1 Subunit, pubmed-meshheading:15824852-Culture Media, Serum-Free, pubmed-meshheading:15824852-DNA, pubmed-meshheading:15824852-Dose-Response Relationship, Drug, pubmed-meshheading:15824852-Ghrelin, pubmed-meshheading:15824852-Immunohistochemistry, pubmed-meshheading:15824852-Leptin, pubmed-meshheading:15824852-Neoplasm Proteins, pubmed-meshheading:15824852-Osteoblasts, pubmed-meshheading:15824852-Osteocalcin, pubmed-meshheading:15824852-Peptide Hormones, pubmed-meshheading:15824852-RNA, Messenger, pubmed-meshheading:15824852-Rats, pubmed-meshheading:15824852-Rats, Sprague-Dawley, pubmed-meshheading:15824852-Receptors, G-Protein-Coupled, pubmed-meshheading:15824852-Receptors, Ghrelin, pubmed-meshheading:15824852-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:15824852-Time Factors, pubmed-meshheading:15824852-Transcription Factors
pubmed:year
2005
pubmed:articleTitle
Ghrelin directly regulates bone formation.
pubmed:affiliation
Molecular Genetics, Institute of Life Science, Kurume University, Kurume, Fukuoka, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't