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rdf:type |
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lifeskim:mentions |
umls-concept:C0007589,
umls-concept:C0007634,
umls-concept:C0031437,
umls-concept:C0080202,
umls-concept:C0086418,
umls-concept:C0220905,
umls-concept:C0301872,
umls-concept:C1257975,
umls-concept:C1314939,
umls-concept:C1332714,
umls-concept:C1511938,
umls-concept:C1704675
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pubmed:issue |
4
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pubmed:dateCreated |
2005-4-11
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pubmed:abstractText |
Experimental evidence and preliminary clinical studies have demonstrated that human mesenchymal stem cells (MSC) have an important immune modulatory function in the setting of allogeneic hematopoietic stem cell (HSC) transplantation. We extended the evaluation of mechanisms responsible for the immune regulatory effect derived from the interaction of human MSC with cells involved in alloantigen-specific immune response in mixed lymphocyte culture (MLC).
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1592-8721
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pubmed:author |
pubmed-author:CometaAngelaA,
pubmed-author:ComoliPatriziaP,
pubmed-author:DaudtLianeL,
pubmed-author:FrassoniFrancescoF,
pubmed-author:IbaticiAdalbertoA,
pubmed-author:LocatelliFrancoF,
pubmed-author:MaccarioRitaR,
pubmed-author:MontagnaDanielaD,
pubmed-author:MorettaAntoniaA,
pubmed-author:PiaggioGiovannaG,
pubmed-author:PodestàMarinaM,
pubmed-author:PozziSarahS
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pubmed:issnType |
Electronic
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
516-25
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15820948-Antibody Formation,
pubmed-meshheading:15820948-CD4-Positive T-Lymphocytes,
pubmed-meshheading:15820948-Cell Communication,
pubmed-meshheading:15820948-Cell Differentiation,
pubmed-meshheading:15820948-Epitopes,
pubmed-meshheading:15820948-Flow Cytometry,
pubmed-meshheading:15820948-Gene Expression Regulation,
pubmed-meshheading:15820948-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:15820948-Humans,
pubmed-meshheading:15820948-Immunosuppression,
pubmed-meshheading:15820948-Isoantigens,
pubmed-meshheading:15820948-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:15820948-Mesenchymal Stem Cells,
pubmed-meshheading:15820948-Phenotype,
pubmed-meshheading:15820948-T-Lymphocyte Subsets
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pubmed:year |
2005
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pubmed:articleTitle |
Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype.
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pubmed:affiliation |
Laboratorio di Immunologia dei Trapianti, Oncoematologia Pediatrica, IRCCS Policlinico San Matteo, P.le Golgi 19, 27100 Pavia, Italy. r.maccario@smatteo.pv.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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