Source:http://linkedlifedata.com/resource/pubmed/id/15820391
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2005-4-11
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pubmed:abstractText |
Temporal aspects of intracellular calcium signaling are particularly important in activity-dependent regulation of gene expression in neurons. This review traces calcium-dependent intracellular signaling from the membrane to the nucleus in response to action-potential firing, and considers how specific genes are regulated by specific patterns of impulse firing. Modes of calcium influx, calcium-dependent protein kinases, transcription factors, individual genes, and genomic analysis are examined, with particular emphasis on the importance of temporal aspects of calcium dynamics in regulating these processes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0143-4160
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
433-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15820391-Action Potentials,
pubmed-meshheading:15820391-Animals,
pubmed-meshheading:15820391-Calcium,
pubmed-meshheading:15820391-Calcium Signaling,
pubmed-meshheading:15820391-Gene Expression Regulation,
pubmed-meshheading:15820391-Humans,
pubmed-meshheading:15820391-Intracellular Fluid
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pubmed:year |
2005
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pubmed:articleTitle |
Temporal integration of intracellular Ca2+ signaling networks in regulating gene expression by action potentials.
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pubmed:affiliation |
Nervous System Development and Plasticity Section, National Institutes of Health, NICHD, Bldg. 35, Room 2A211, MSC 3713, 35 Lincoln Drive, Bethesda, MD 20892, USA. fieldsd@mail.nih.gov
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review
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