Source:http://linkedlifedata.com/resource/pubmed/id/15820084
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2005-4-11
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pubmed:abstractText |
Genetic factors are believed to play a role in the individual susceptibility to chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism (SNP) of tumour necrosis factor-alpha (TNF-alpha) has been reported but inconsistent results may arise from different populations and phenotypes of COPD. There are only a few published studies of interleukin-13 (IL-13) SNPs on COPD. The SNPs of TNF-alpha and IL-13 have not been studied in the Chinese population. This research was conducted to study the frequencies of IL-13 gene promoter 1055 (IL-13-1055) and TNF-alpha gene-308 polymorphisms in the patients with COPD and to investigate the effect of those genetic polymorphisms on COPD in the Chinese population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0366-6999
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
541-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15820084-Adult,
pubmed-meshheading:15820084-Aged,
pubmed-meshheading:15820084-China,
pubmed-meshheading:15820084-Female,
pubmed-meshheading:15820084-Genotype,
pubmed-meshheading:15820084-Humans,
pubmed-meshheading:15820084-Interleukin-13,
pubmed-meshheading:15820084-Male,
pubmed-meshheading:15820084-Middle Aged,
pubmed-meshheading:15820084-Polymorphism, Genetic,
pubmed-meshheading:15820084-Pulmonary Disease, Chronic Obstructive,
pubmed-meshheading:15820084-Tumor Necrosis Factor-alpha
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pubmed:year |
2005
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pubmed:articleTitle |
Association of gene polymorphisms of tumour necrosis factor-alpha and interleukin-13 with chronic obstructive pulmonary disease in Han nationality in Beijing.
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pubmed:affiliation |
Department of Pulmonary Disease, Peking University Third Hospital, Beijing 100083, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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