Source:http://linkedlifedata.com/resource/pubmed/id/15808693
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2005-4-5
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pubmed:abstractText |
Hyperacute rejection (HAR) is one of the principal obstacles to successful xenotransplantation. Homozygous alpha-1,3-galactosyltransferase knockout (GalT-KO) miniature swine now offer the prospect of overcoming this barrier to xenotransplantation. In this study, the short-term function of GalT-KO swine lungs was evaluated in a well-established ex vivo model of swine-to-human lung xenotransplantation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0041-1345
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
512-3
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pubmed:meshHeading |
pubmed-meshheading:15808693-Acute Disease,
pubmed-meshheading:15808693-Animals,
pubmed-meshheading:15808693-Galactosyltransferases,
pubmed-meshheading:15808693-Gene Deletion,
pubmed-meshheading:15808693-Graft Rejection,
pubmed-meshheading:15808693-Humans,
pubmed-meshheading:15808693-Lung Transplantation,
pubmed-meshheading:15808693-Respiratory Function Tests,
pubmed-meshheading:15808693-Swine,
pubmed-meshheading:15808693-Transplantation, Heterologous
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pubmed:articleTitle |
Hyperacute rejection is attenuated in GalT knockout swine lungs perfused ex vivo with human blood.
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pubmed:affiliation |
Department of Surgery, Division of Thoracic Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, USA.
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pubmed:publicationType |
Journal Article
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