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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-4-5
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pubmed:abstractText |
CYP3A is the major enzyme responsible for metabolism of the calcineurin inhibitors cyclosporine (CsA) and tacrolimus. Our objective was to determine the relationship between genetic polymorphisms of CYP3A5 with respect to interindividual variability in CsA and tacrolimus pharmacokinetics.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0041-1345
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
178-81
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15808586-Base Sequence,
pubmed-meshheading:15808586-China,
pubmed-meshheading:15808586-Cyclosporine,
pubmed-meshheading:15808586-Cytochrome P-450 CYP3A,
pubmed-meshheading:15808586-Cytochrome P-450 Enzyme System,
pubmed-meshheading:15808586-DNA Primers,
pubmed-meshheading:15808586-Female,
pubmed-meshheading:15808586-Genotype,
pubmed-meshheading:15808586-Humans,
pubmed-meshheading:15808586-Immunosuppressive Agents,
pubmed-meshheading:15808586-Kidney Transplantation,
pubmed-meshheading:15808586-Male,
pubmed-meshheading:15808586-Polymerase Chain Reaction,
pubmed-meshheading:15808586-Polymorphism, Genetic,
pubmed-meshheading:15808586-Tacrolimus
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pubmed:articleTitle |
Genetic polymorphisms of CYP3A5 genes and concentration of the cyclosporine and tacrolimus.
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pubmed:affiliation |
The First Hospital of Tsinghua University, Beijing, China.
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pubmed:publicationType |
Journal Article
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