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pubmed-article:15808485pubmed:dateCreated2005-4-5lld:pubmed
pubmed-article:15808485pubmed:abstractTextThe sulfur analogue of sphingomyelin was designed and stereoselectively synthesized from S-benzyl-N-Boc-cysteine. The introduction of the phosphoryl choline moiety was successfully achieved by our own method using 2-bromoethyl dimethyl phosphite and carbon tetrabromide followed by a trimethylamine treatment. The synthesized compound proved to be a useful substrate for monitoring the enzyme activity of sphingomyelinase by detecting the liberated thiol group with a thiol-sensitive reagent.lld:pubmed
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pubmed-article:15808485pubmed:authorpubmed-author:IkedaKiyoshiKlld:pubmed
pubmed-article:15808485pubmed:authorpubmed-author:KatsumuraShig...lld:pubmed
pubmed-article:15808485pubmed:authorpubmed-author:HakogiToshika...lld:pubmed
pubmed-article:15808485pubmed:authorpubmed-author:FujiiShinobuSlld:pubmed
pubmed-article:15808485pubmed:authorpubmed-author:MoritaMichioMlld:pubmed
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pubmed-article:15808485pubmed:pagination2141-4lld:pubmed
pubmed-article:15808485pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:15808485pubmed:year2005lld:pubmed
pubmed-article:15808485pubmed:articleTitleSynthesis of sphingomyelin sulfur analogue and its behavior toward sphingomyelinase.lld:pubmed
pubmed-article:15808485pubmed:affiliationSchool of Science, Kwansei Gakuin University, Gakuen, Sanda, Hyogo 669-1337, Japan.lld:pubmed
pubmed-article:15808485pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15808485pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed