Source:http://linkedlifedata.com/resource/pubmed/id/15808485
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2005-4-5
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pubmed:abstractText |
The sulfur analogue of sphingomyelin was designed and stereoselectively synthesized from S-benzyl-N-Boc-cysteine. The introduction of the phosphoryl choline moiety was successfully achieved by our own method using 2-bromoethyl dimethyl phosphite and carbon tetrabromide followed by a trimethylamine treatment. The synthesized compound proved to be a useful substrate for monitoring the enzyme activity of sphingomyelinase by detecting the liberated thiol group with a thiol-sensitive reagent.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2141-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading | |
pubmed:year |
2005
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pubmed:articleTitle |
Synthesis of sphingomyelin sulfur analogue and its behavior toward sphingomyelinase.
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pubmed:affiliation |
School of Science, Kwansei Gakuin University, Gakuen, Sanda, Hyogo 669-1337, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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