Linked Life Data

15806369

Source:http://linkedlifedata.com/resource/pubmed/id/15806369

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:15806369rdf:typepubmed:Citationlld:pubmed
pubmed-article:15806369lifeskim:mentionsumls-concept:C0030705lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C0007113lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C1704632lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C0871261lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C1517927lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C2911692lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C1706817lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C1707455lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C0024485lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C0032743lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C0681842lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C0814225lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C0600558lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C1517324lld:lifeskim
pubmed-article:15806369lifeskim:mentionsumls-concept:C0205179lld:lifeskim
pubmed-article:15806369pubmed:issue8lld:pubmed
pubmed-article:15806369pubmed:dateCreated2005-7-21lld:pubmed
pubmed-article:15806369pubmed:abstractTextThe aim of this study was to compare CT, MRI and FDG-PET in the prediction of outcome of neoadjuvant radiochemotherapy in patients with locally advanced primary rectal cancer. A total of 23 patients with T3/4 rectal cancer underwent a preoperative radiochemotherapy combined with regional hyperthermia. Staging was performed using four-slice CT (n=23), 1.5-T MRI (n=10), and (18)F-FDG-PET (n=23) before and 2-4 weeks after completion of neoadjuvant treatment. Response criteria were a change in T category and tumour volume for CT and MRI and a change in glucose uptake (standard uptake value) within the tumour for FDG-PET. Imaging results were compared with those of pretherapy endorectal ultrasound and histopathological findings. Histopathology showed a response to neoadjuvant therapy in 13 patients whereas 10 patients were classified as nonresponders. The mean SUV reduction in responders (60+/-14%) was significantly higher than in nonresponders (37+/-31%; P=0.030). The sensitivity and specificity of FDG-PET in identifying response was 100% (CT 54%, MRI 71%) and 60% (CT 80%, MRT 67%). Positive and negative predictive values were 77% (CT 78%, MRI 83%) and 100% (CT 57%, MRI 50%) (PET P=0.002, CT P=0.197, MRI P=0.500). These results suggest that FDG-PET is superior to CT and MRI in predicting response to preoperative multimodal treatment of locally advanced primary rectal cancer.lld:pubmed
pubmed-article:15806369pubmed:languageenglld:pubmed
pubmed-article:15806369pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15806369pubmed:citationSubsetIMlld:pubmed
pubmed-article:15806369pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15806369pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15806369pubmed:statusMEDLINElld:pubmed
pubmed-article:15806369pubmed:monthAuglld:pubmed
pubmed-article:15806369pubmed:issn0938-7994lld:pubmed
pubmed-article:15806369pubmed:authorpubmed-author:FelixRRlld:pubmed
pubmed-article:15806369pubmed:authorpubmed-author:RaoDDlld:pubmed
pubmed-article:15806369pubmed:authorpubmed-author:RufJJlld:pubmed
pubmed-article:15806369pubmed:authorpubmed-author:WustPPlld:pubmed
pubmed-article:15806369pubmed:authorpubmed-author:HünerbeinMMlld:pubmed
pubmed-article:15806369pubmed:authorpubmed-author:HildebrandtBBlld:pubmed
pubmed-article:15806369pubmed:authorpubmed-author:AmthauerHHlld:pubmed
pubmed-article:15806369pubmed:authorpubmed-author:DeneckeTTlld:pubmed
pubmed-article:15806369pubmed:authorpubmed-author:GutberletMMlld:pubmed
pubmed-article:15806369pubmed:authorpubmed-author:HoffmannK-TKTlld:pubmed
pubmed-article:15806369pubmed:issnTypePrintlld:pubmed
pubmed-article:15806369pubmed:volume15lld:pubmed
pubmed-article:15806369pubmed:ownerNLMlld:pubmed
pubmed-article:15806369pubmed:authorsCompleteYlld:pubmed
pubmed-article:15806369pubmed:pagination1658-66lld:pubmed
pubmed-article:15806369pubmed:dateRevised2006-11-15lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:meshHeadingpubmed-meshheading:15806369...lld:pubmed
pubmed-article:15806369pubmed:year2005lld:pubmed
pubmed-article:15806369pubmed:articleTitleComparison of CT, MRI and FDG-PET in response prediction of patients with locally advanced rectal cancer after multimodal preoperative therapy: is there a benefit in using functional imaging?lld:pubmed
pubmed-article:15806369pubmed:affiliationKlinik für Strahlenheilkunde und PET-Zentrum Berlin Campus Virchow Klinikum, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, 13353, Germany. timm.denecke@charite.delld:pubmed
pubmed-article:15806369pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15806369pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:15806369pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
pubmed-article:15806369pubmed:publicationTypeClinical Trial, Phase IIIlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15806369lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15806369lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15806369lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15806369lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15806369lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15806369lld:pubmed