15801939

Source:http://linkedlifedata.com/resource/pubmed/id/15801939

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0012373, umls-concept:C0017262, umls-concept:C0021853, umls-concept:C0033684, umls-concept:C0035696, umls-concept:C0059563, umls-concept:C0086418, umls-concept:C0185117, umls-concept:C0441655, umls-concept:C1515655, umls-concept:C2911684
pubmed:issue	4
pubmed:dateCreated	2005-4-1
pubmed:abstractText	To determine the effect of diltiazem on intestinal CYP3A activity and protein and mRNA expression in vivo in healthy subjects.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/AG 13718, http://linkedlifedata.com/resource/pubmed/grant/FDT-001726, http://linkedlifedata.com/resource/pubmed/grant/M01-RR00750, http://linkedlifedata.com/resource/pubmed/grant/T32GM08425
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7503323
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A4 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Calcium Channel Blockers, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System, http://linkedlifedata.com/resource/pubmed/chemical/Diltiazem, http://linkedlifedata.com/resource/pubmed/chemical/Oxidoreductases, N-Demethylating, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	0306-5251
pubmed:author	pubmed-author:AsgharAA, pubmed-author:ChalasaniNN, pubmed-author:HallS DSD, pubmed-author:HammarAA, pubmed-author:HorlanderJJ, pubmed-author:KolwankarDD, pubmed-author:PintoA GAG
pubmed:issnType	Print
pubmed:volume	59
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	440-6
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:15801939-Adult, pubmed-meshheading:15801939-Aged, pubmed-meshheading:15801939-Aryl Hydrocarbon Hydroxylases, pubmed-meshheading:15801939-Calcium Channel Blockers, pubmed-meshheading:15801939-Cytochrome P-450 CYP3A, pubmed-meshheading:15801939-Cytochrome P-450 Enzyme System, pubmed-meshheading:15801939-Diltiazem, pubmed-meshheading:15801939-Duodenum, pubmed-meshheading:15801939-Female, pubmed-meshheading:15801939-Humans, pubmed-meshheading:15801939-Immunoblotting, pubmed-meshheading:15801939-Male, pubmed-meshheading:15801939-Middle Aged, pubmed-meshheading:15801939-Oxidoreductases, N-Demethylating, pubmed-meshheading:15801939-Polymerase Chain Reaction, pubmed-meshheading:15801939-RNA, Messenger
pubmed:year	2005
pubmed:articleTitle	Diltiazem inhibits human intestinal cytochrome P450 3A (CYP3A) activity in vivo without altering the expression of intestinal mRNA or protein.
pubmed:affiliation	Indiana University School of Medicine, Department of Medicine, Division of Clinical Pharmacology, Wishard Memorial Hospital, Indianapolis, Indiana, USA.
pubmed:publicationType	Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Randomized Controlled Trial, Research Support, N.I.H., Extramural