15801938

Source:http://linkedlifedata.com/resource/pubmed/id/15801938

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017245, umls-concept:C0031327, umls-concept:C0043031, umls-concept:C0851347, umls-concept:C1280500, umls-concept:C1708335
pubmed:issue	4
pubmed:dateCreated	2005-4-1
pubmed:abstractText	Case reports suggest that gemfobrozil can increase the anticoagulant effect of warfarin. Because gemfibrozil inhibits CYP2C9 in vitro, we studied its effects on the pharmacokinetics and pharmacodynamics of racemic warfarin.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7503323
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anticoagulants, http://linkedlifedata.com/resource/pubmed/chemical/Gemfibrozil, http://linkedlifedata.com/resource/pubmed/chemical/Hypolipidemic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Warfarin
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	0306-5251
pubmed:author	pubmed-author:BackmanJanne TJT, pubmed-author:LiljaJari JJJ, pubmed-author:NeuvonenPertti JPJ
pubmed:issnType	Print
pubmed:volume	59
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	433-9
pubmed:dateRevised	2010-11-18
pubmed:meshHeading	pubmed-meshheading:15801938-Adult, pubmed-meshheading:15801938-Anticoagulants, pubmed-meshheading:15801938-Area Under Curve, pubmed-meshheading:15801938-Blood Coagulation, pubmed-meshheading:15801938-Chromatography, High Pressure Liquid, pubmed-meshheading:15801938-Cross-Over Studies, pubmed-meshheading:15801938-Female, pubmed-meshheading:15801938-Gemfibrozil, pubmed-meshheading:15801938-Humans, pubmed-meshheading:15801938-Hypolipidemic Agents, pubmed-meshheading:15801938-Male, pubmed-meshheading:15801938-Partial Thromboplastin Time, pubmed-meshheading:15801938-Warfarin
pubmed:year	2005
pubmed:articleTitle	Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of racemic warfarin in healthy subjects.
pubmed:affiliation	Department of Clinical Pharmacology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland. jari.lilja@hus.fi
pubmed:publicationType	Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't