Source:http://linkedlifedata.com/resource/pubmed/id/15800982
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
13
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pubmed:dateCreated |
2005-3-31
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pubmed:abstractText |
Considerable attention is focused on polymorphisms in the gene encoding transforming growth factor-beta1 (TGF-beta1), a multifunctional cytokine that is in turn a potent growth inhibitor involved in wound healing and differentiation. In humans, it promotes the pathogenesis of organ fibrosis, atherosclerosis, cancer, autoimmune and inflammatory diseases, keloid disease, and hypertrophic scarring. For this reason, much emphasis has been placed on studies elucidating the impact of TGF-beta1 and its gene variations for the susceptibility and pathogenesis of these diseases. Unfortunately, some studies have serious limitations.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1007-9327
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1929-36
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15800982-Asian Continental Ancestry Group,
pubmed-meshheading:15800982-Base Sequence,
pubmed-meshheading:15800982-European Continental Ancestry Group,
pubmed-meshheading:15800982-Genotype,
pubmed-meshheading:15800982-Hepatitis C, Chronic,
pubmed-meshheading:15800982-Humans,
pubmed-meshheading:15800982-Liver Cirrhosis,
pubmed-meshheading:15800982-Molecular Sequence Data,
pubmed-meshheading:15800982-Polymorphism, Genetic,
pubmed-meshheading:15800982-Transforming Growth Factor beta,
pubmed-meshheading:15800982-Transforming Growth Factor beta1
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pubmed:year |
2005
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pubmed:articleTitle |
Transforming growth factor-beta1 gene polymorphisms are associated with progression of liver fibrosis in Caucasians with chronic hepatitis C infection.
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pubmed:affiliation |
Department of Laboratory Medicine, Changzheng Hospital, Second Military Medical University, Shanghai, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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