|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2005-3-30
|
|
pubmed:abstractText |
Cardiac allograft vasculopathy (CAV) limits survival after cardiac transplantation. Tumor necrosis factor-alpha (TNF-alpha) may be a key factor in the development of CAV. Two bi-allelic polymorphisms associated with high TNF-alpha production have been identified in the TNF gene locus, TNFA1/2, at position -308 and TNFB1/2 at +252. We hypothesized that recipient TNFA2 and TNFB2 homozygosity is associated with the development of CAV after heart transplantation.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
1053-2498
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
24
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
433-8
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15797745-Adult,
pubmed-meshheading:15797745-Coronary Angiography,
pubmed-meshheading:15797745-Coronary Artery Disease,
pubmed-meshheading:15797745-Coronary Vessels,
pubmed-meshheading:15797745-Female,
pubmed-meshheading:15797745-Follow-Up Studies,
pubmed-meshheading:15797745-Gene Frequency,
pubmed-meshheading:15797745-Genetic Markers,
pubmed-meshheading:15797745-Graft Rejection,
pubmed-meshheading:15797745-Graft Survival,
pubmed-meshheading:15797745-Heart Transplantation,
pubmed-meshheading:15797745-Humans,
pubmed-meshheading:15797745-Immunosuppressive Agents,
pubmed-meshheading:15797745-Male,
pubmed-meshheading:15797745-Middle Aged,
pubmed-meshheading:15797745-Polymerase Chain Reaction,
pubmed-meshheading:15797745-Polymorphism, Genetic,
pubmed-meshheading:15797745-Prospective Studies,
pubmed-meshheading:15797745-Survival Rate,
pubmed-meshheading:15797745-Transplantation, Homologous,
pubmed-meshheading:15797745-Tumor Necrosis Factor-alpha
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Tumor necrosis factor gene polymorphism and cardiac allograft vasculopathy.
|
|
pubmed:affiliation |
Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Göteborg, Sweden.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study
|
