Source:http://linkedlifedata.com/resource/pubmed/id/15795908
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
2005-4-4
|
pubmed:abstractText |
Primary mediastinal B-cell lymphoma (PMBCL) is a clinicopathological entity with aggressive behavior. Retrospective evaluation suggests the need for intensive chemotherapy programs. From 1997 to February 2003, a total of 11 cases of previously untreated PMBCL with sclerosis were treated at our institution with 5 courses of intensified CHOP (ICHOP) regimen and mediastinal irradiation. Three patients were submitted to high-dose chemotherapy with peripheral-blood stem-cell support, followed by radiotherapy, because of intermediate-risk age-adjusted International Prognostic Index at diagnosis. After a median follow up of 30 months, all patients but one are in continuous complete remission (CR), and overall survival is 100%.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0361-8609
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
78
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
312-3
|
pubmed:dateRevised |
2006-4-24
|
pubmed:meshHeading |
pubmed-meshheading:15795908-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:15795908-Combined Modality Therapy,
pubmed-meshheading:15795908-Cyclophosphamide,
pubmed-meshheading:15795908-Dose-Response Relationship, Drug,
pubmed-meshheading:15795908-Doxorubicin,
pubmed-meshheading:15795908-Follow-Up Studies,
pubmed-meshheading:15795908-Humans,
pubmed-meshheading:15795908-Lymphoma, B-Cell,
pubmed-meshheading:15795908-Mediastinal Neoplasms,
pubmed-meshheading:15795908-Prednisone,
pubmed-meshheading:15795908-Recurrence,
pubmed-meshheading:15795908-Treatment Outcome,
pubmed-meshheading:15795908-Vincristine
|
pubmed:year |
2005
|
pubmed:articleTitle |
Primary mediastinal B-cell lymphoma with sclerosis: report of 11 cases treated with intensified-CHOP plus radiotherapy.
|
pubmed:affiliation |
Department of Medical Oncology and Hematology, Istituto Clinico Humanitas, Rozzano, Milan, Italy. licia.siracusano@humanitas.it
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|