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pubmed-article:15790988pubmed:abstractTextThe pulmonary phenotype in patients with cystic fibrosis (CF), even in those with the same CF transmembrane conductance regulator (CFTR) genotype, is variable and must therefore be influenced by secondary genetic factors as well as environmental factors. Possible candidate genes that modulate the CF lung phenotype may include proinflammatory cytokines. One such protein is tumour necrosis factor alpha (TNFalpha), a member of the immune system.lld:pubmed
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pubmed-article:15790988pubmed:articleTitleAssociation of tumour necrosis factor alpha variants with the CF pulmonary phenotype.lld:pubmed
pubmed-article:15790988pubmed:affiliationDepartment for Human Genetics, KULeuven, Herestraat 49, O&N6, 3000 Leuven, Belgium.lld:pubmed
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