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pubmed-article:15788695pubmed:abstractTextAcute myeloid leukemia (AML) is considered a stem cell disease. Incomplete chemotherapeutic eradication of leukemic CD34+38- stem cells is likely to result in disease relapse. The purpose of this study was to investigate the role of the breast cancer resistance protein (BCRP/ATP-binding cassette, subfamily G, member 2) in drug resistance of leukemic stem cells and the effect of its modulation on stem cell eradication in AML.lld:pubmed
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pubmed-article:15788695pubmed:articleTitleBreast cancer resistance protein in drug resistance of primitive CD34+38- cells in acute myeloid leukemia.lld:pubmed
pubmed-article:15788695pubmed:affiliationDepartment of Hematology and Central Hematology Laboratory, University Medical Center Nijmegen, St. Radboud, 6500 HB Nijmegen, the Netherlands. h.raajmakers@chl.umcn.nllld:pubmed
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