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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2005-3-24
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pubmed:abstractText |
Acute myeloid leukemia (AML) is considered a stem cell disease. Incomplete chemotherapeutic eradication of leukemic CD34+38- stem cells is likely to result in disease relapse. The purpose of this study was to investigate the role of the breast cancer resistance protein (BCRP/ATP-binding cassette, subfamily G, member 2) in drug resistance of leukemic stem cells and the effect of its modulation on stem cell eradication in AML.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ABCG2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/ADP-ribosyl Cyclase,
http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD34,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD38,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/CD38 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Mitoxantrone,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2436-44
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15788695-ADP-ribosyl Cyclase,
pubmed-meshheading:15788695-ATP-Binding Cassette Transporters,
pubmed-meshheading:15788695-Acute Disease,
pubmed-meshheading:15788695-Adult,
pubmed-meshheading:15788695-Aged,
pubmed-meshheading:15788695-Antigens, CD,
pubmed-meshheading:15788695-Antigens, CD34,
pubmed-meshheading:15788695-Antigens, CD38,
pubmed-meshheading:15788695-Antineoplastic Agents,
pubmed-meshheading:15788695-Bone Marrow,
pubmed-meshheading:15788695-Drug Resistance, Multiple,
pubmed-meshheading:15788695-Drug Resistance, Neoplasm,
pubmed-meshheading:15788695-Female,
pubmed-meshheading:15788695-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15788695-Humans,
pubmed-meshheading:15788695-Leukemia, Myeloid,
pubmed-meshheading:15788695-Male,
pubmed-meshheading:15788695-Membrane Glycoproteins,
pubmed-meshheading:15788695-Middle Aged,
pubmed-meshheading:15788695-Mitoxantrone,
pubmed-meshheading:15788695-Neoplasm Proteins,
pubmed-meshheading:15788695-Stem Cells,
pubmed-meshheading:15788695-Tumor Cells, Cultured
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pubmed:year |
2005
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pubmed:articleTitle |
Breast cancer resistance protein in drug resistance of primitive CD34+38- cells in acute myeloid leukemia.
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pubmed:affiliation |
Department of Hematology and Central Hematology Laboratory, University Medical Center Nijmegen, St. Radboud, 6500 HB Nijmegen, the Netherlands. h.raajmakers@chl.umcn.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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