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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0033325,
umls-concept:C0078058,
umls-concept:C0174383,
umls-concept:C0178587,
umls-concept:C0185117,
umls-concept:C0221198,
umls-concept:C0442027,
umls-concept:C0449258,
umls-concept:C0812201,
umls-concept:C1171892,
umls-concept:C1514391,
umls-concept:C1707520,
umls-concept:C2350570,
umls-concept:C2911684
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pubmed:issue |
6
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pubmed:dateCreated |
2005-3-24
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pubmed:abstractText |
Identification of molecular changes characteristic of development and progression of oral cancer are of paramount importance for effective intervention. Stromelysin 3 (MMP11) is a unique matrix metalloproteinase shown to have dual function during cancer progression. The transcription factor Ets-1 and vascular endothelial growth factor (VEGF) are important proangiogenic factors in cancer. This study was designed to test the hypothesis that concomitant expression of stromelysin 3, Ets-1, and/or VEGF affects the development, progression, and prognosis of oral cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ETS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 11,
http://linkedlifedata.com/resource/pubmed/chemical/Metalloendopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Protein c-ets-1,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-ets,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/VEGFA protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2272-84
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15788677-Adult,
pubmed-meshheading:15788677-Aged,
pubmed-meshheading:15788677-Aged, 80 and over,
pubmed-meshheading:15788677-Carcinoma, Squamous Cell,
pubmed-meshheading:15788677-Case-Control Studies,
pubmed-meshheading:15788677-Disease Progression,
pubmed-meshheading:15788677-Female,
pubmed-meshheading:15788677-Humans,
pubmed-meshheading:15788677-Male,
pubmed-meshheading:15788677-Matrix Metalloproteinase 11,
pubmed-meshheading:15788677-Metalloendopeptidases,
pubmed-meshheading:15788677-Middle Aged,
pubmed-meshheading:15788677-Mouth Mucosa,
pubmed-meshheading:15788677-Mouth Neoplasms,
pubmed-meshheading:15788677-Neoplasm Invasiveness,
pubmed-meshheading:15788677-Neoplasm Staging,
pubmed-meshheading:15788677-Neovascularization, Pathologic,
pubmed-meshheading:15788677-Precancerous Conditions,
pubmed-meshheading:15788677-Prognosis,
pubmed-meshheading:15788677-Protein-Tyrosine Kinases,
pubmed-meshheading:15788677-Proto-Oncogene Protein c-ets-1,
pubmed-meshheading:15788677-Proto-Oncogene Proteins,
pubmed-meshheading:15788677-Proto-Oncogene Proteins c-ets,
pubmed-meshheading:15788677-Survival Rate,
pubmed-meshheading:15788677-Transcription Factors,
pubmed-meshheading:15788677-Vascular Endothelial Growth Factor A
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pubmed:year |
2005
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pubmed:articleTitle |
Stromelysin 3, Ets-1, and vascular endothelial growth factor expression in oral precancerous and cancerous lesions: correlation with microvessel density, progression, and prognosis.
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pubmed:affiliation |
Department of Biochemistry, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110-029, India.
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pubmed:publicationType |
Journal Article
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