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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1992-6-10
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pubmed:abstractText |
We report a patient with systemic plasmacytosis with polyclonal hyperimmunoglobulinemia who at presentation showed a blood and bone marrow picture suggestive of plasma cell leukemia. A 78-year-old woman was admitted to our hospital because of marked hepatosplenomegaly and generalized lymphadenopathy. She had leukocytosis with 42% plasmacytes, and plasma cells were increased also in her bone marrow (32.6%). She had marked polyclonal hyperimmunoglobulinemia with increased IgG, IgA and IgE. IgM and IgD were normal. She complained of cough and dyspnea. Her general condition was too poor to remove a lymph node for pathological examination. After treatment with daunorubicin, vincristine and prednisolone (DVP), her lymphadenopathy diminished rapidly, the immunoglobulins decreased and the plasma cells in her blood disappeared. She achieved a complete remission and has been in good condition without further treatment for 24 months.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Daunorubicin,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin A,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Prednisolone,
http://linkedlifedata.com/resource/pubmed/chemical/Vincristine
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0485-1439
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
377-83
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1578643-Aged,
pubmed-meshheading:1578643-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:1578643-Blood Cell Count,
pubmed-meshheading:1578643-Daunorubicin,
pubmed-meshheading:1578643-Female,
pubmed-meshheading:1578643-Humans,
pubmed-meshheading:1578643-Hypergammaglobulinemia,
pubmed-meshheading:1578643-Immunoglobulin A,
pubmed-meshheading:1578643-Immunoglobulin G,
pubmed-meshheading:1578643-Leukemia, Plasma Cell,
pubmed-meshheading:1578643-Plasma Cells,
pubmed-meshheading:1578643-Prednisolone,
pubmed-meshheading:1578643-Vincristine
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pubmed:year |
1992
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pubmed:articleTitle |
[Systemic plasmacytosis with polyclonal hypergammaglobulinemia and numerous plasma cells in the blood].
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pubmed:affiliation |
Department of Internal Medicine, Nagaoka Red Cross Hospital.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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