Source:http://linkedlifedata.com/resource/pubmed/id/15782573
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2005-3-23
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pubmed:abstractText |
A 46-year-old man was referred to our hospital for the treatment of lung cancer. Computed tomography showed a well-defined tumor mass that was 50x45 mm in size and contained a trabecular pattern of calcification. Since he was diagnosed as having a primary lung adenocarcinoma (clinical stage IB), a left upper lobectomy with mediastinal lymph node dissection was performed. Histologically, the tumor was a poorly differentiated adenocarcinoma with rich fibrous stroma, in which there were island-shaped bone formation lesions. An immunohistochemical examination showed the expression of bone morphogenic protein-2 within tumor cells, which induce and stimulate bone formation. This finding may elucidate a possible mechanism of heterotopic bone formation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1344-4964
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
102-5
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pubmed:meshHeading |
pubmed-meshheading:15782573-Adenocarcinoma,
pubmed-meshheading:15782573-Bone Morphogenetic Proteins,
pubmed-meshheading:15782573-Humans,
pubmed-meshheading:15782573-Immunohistochemistry,
pubmed-meshheading:15782573-Lung Neoplasms,
pubmed-meshheading:15782573-Male,
pubmed-meshheading:15782573-Middle Aged,
pubmed-meshheading:15782573-Ossification, Heterotopic
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pubmed:year |
2005
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pubmed:articleTitle |
Primary lung adenocarcinoma with heterotopic bone formation.
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pubmed:affiliation |
Department of Thoracic Surgery, Nagoya University School of Medicine, Nagoya, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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