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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2005-3-22
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pubmed:abstractText |
8-hydroxydeoxyguanosine (8-OHdG) has been used to evaluate oxidative stress. The authors investigated urinary 8-OHdG levels in 72 patients with Parkinson disease (PD) and in normal and disease control groups. The mean urinary 8-OHdG increased with the stage of PD and was not influenced by the current dose of DOPA. Our results suggest that urinary 8-OHdG is a potentially useful biomarker for evaluating the progression of PD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1526-632X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
22
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1081-3
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pubmed:meshHeading |
pubmed-meshheading:15781836-Adult,
pubmed-meshheading:15781836-Aged,
pubmed-meshheading:15781836-Aged, 80 and over,
pubmed-meshheading:15781836-Biological Markers,
pubmed-meshheading:15781836-Brain,
pubmed-meshheading:15781836-Creatinine,
pubmed-meshheading:15781836-Deoxyguanosine,
pubmed-meshheading:15781836-Dihydroxyphenylalanine,
pubmed-meshheading:15781836-Disease Progression,
pubmed-meshheading:15781836-Dopamine Agents,
pubmed-meshheading:15781836-Dose-Response Relationship, Drug,
pubmed-meshheading:15781836-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15781836-Female,
pubmed-meshheading:15781836-Humans,
pubmed-meshheading:15781836-Male,
pubmed-meshheading:15781836-Middle Aged,
pubmed-meshheading:15781836-Oxidative Stress,
pubmed-meshheading:15781836-Parkinson Disease,
pubmed-meshheading:15781836-Predictive Value of Tests
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pubmed:year |
2005
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pubmed:articleTitle |
Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease.
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pubmed:affiliation |
Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article
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