Source:http://linkedlifedata.com/resource/pubmed/id/15781389
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2005-3-22
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pubmed:abstractText |
The extracts of Inula britannica have anti-inflammatory, anti-bacterial, anti-hepatitic, and anti-tumor activities. Various sesquiterpene lactones with cytotoxic properties including 1-O-acetylbritannilactone (1) have been isolated from this Chinese medicinal plant. Eight derivatives of 1-O-acetylbritannilactone, (2-O-alkyloxime-3-phenyl)-propionyl-1-O-acetylbritannilactone esters were designed and synthesized. Four of these compounds were tested to show inhibitory activity on the growth of human leukemia HL-60 and cancer Bel-7402 cell lines.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0968-0896
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2783-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15781389-Antineoplastic Agents,
pubmed-meshheading:15781389-Cell Division,
pubmed-meshheading:15781389-Crystallography, X-Ray,
pubmed-meshheading:15781389-Drug Design,
pubmed-meshheading:15781389-Drug Screening Assays, Antitumor,
pubmed-meshheading:15781389-Esters,
pubmed-meshheading:15781389-HL-60 Cells,
pubmed-meshheading:15781389-Humans,
pubmed-meshheading:15781389-Lactones,
pubmed-meshheading:15781389-Models, Molecular,
pubmed-meshheading:15781389-Molecular Conformation
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pubmed:year |
2005
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pubmed:articleTitle |
Design, synthesis, and anti-tumor activity of (2-O-alkyloxime-3-phenyl)-propionyl-1-O-acetylbritannilactone esters.
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pubmed:affiliation |
Xi'an Jiaotong University, Xi'an 710049, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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