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pubmed-article:15780081pubmed:abstractTextAlthough hyperlipidemia is a risk factor for the progression of renal damage, the relationship between increased plasma lipoproteins and glomerular injury is poorly defined. Connective tissue growth factor (CTGF) is emerging as a key determinant of progressive fibrotic diseases and its expression is up-regulated by diabetes. To define the mechanisms through which low-density lipoproteins (LDLs) promote glomerular injury, we evaluated whether LDL can modulate the expression of CTGF and collagen I.lld:pubmed
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pubmed-article:15780081pubmed:articleTitleEvidence for low-density lipoprotein-induced expression of connective tissue growth factor in mesangial cells.lld:pubmed
pubmed-article:15780081pubmed:affiliationDepartment of Medicine, Endocrinology-Diabetes-Medical Genetics, Medical University of South Carolina, Charleston, South Carolina 29425, USA.lld:pubmed
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