Source:http://linkedlifedata.com/resource/pubmed/id/15777982
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2005-3-21
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pubmed:abstractText |
Gefitinib (Iressa, ZD1839) is an orally active inhibitor selective for the epidermal growth factor receptor tyrosine kinase and has shown promise in the treatment of non-small cell lung cancer (NSCLC). There has been no report to date of the effect of gefitinib treatment in patients with small-cell lung cancer (SCLC). Here we report a case of metastatic SCLC that was successfully treated with gefitinib. This case is the first reported of objective clinical response after gefitinib treatment in a patient with SCLC. Our report suggests that treatment with gefitinib is a novel option for a subset of patients with SCLC.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0169-5002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
141-4
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15777982-Administration, Oral,
pubmed-meshheading:15777982-Aged,
pubmed-meshheading:15777982-Antineoplastic Agents,
pubmed-meshheading:15777982-Carcinoma, Small Cell,
pubmed-meshheading:15777982-Female,
pubmed-meshheading:15777982-Humans,
pubmed-meshheading:15777982-Lung Neoplasms,
pubmed-meshheading:15777982-Neoplasm Metastasis,
pubmed-meshheading:15777982-Protein-Tyrosine Kinases,
pubmed-meshheading:15777982-Quinazolines,
pubmed-meshheading:15777982-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
Efficacy of the tyrosine kinase inhibitor gefitinib in a patient with metastatic small cell lung cancer.
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pubmed:affiliation |
Department of Respiratory Medicine, Yamaguchi Prefectural Hospital, 77 Osaki, Hofu, Yamaguchi 0835-4411, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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