Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-3-18
pubmed:abstractText
Osteoclasts are terminally differentiated multinucleated cells which play important roles in not only physiological but also pathophysiological bone resorption. Osteoclastic bone resorption can be divided into several processes; 1) Proliferation of osteoclast precursors on bone surfaces; 2) Differentiation of the precursors into mononuclear osteoclasts; 3) Multinucleation; 4) Adhesion to bone surfaces and cytoskeletal organization (activation); 5) Expanding resorption lacunae by cell migration; 6) Apoptosis. alphavbeta3 integrins, heterodimeric adhesion receptors, are involved in these steps. In this chapter, we discuss this multifunctional molecule from the viewpoint of osteoclasts.
pubmed:language
jpn
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
May
pubmed:issn
0917-5857
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
607-14
pubmed:dateRevised
2006-11-15
pubmed:year
2002
pubmed:articleTitle
[Osteoclasts and alphavbeta3 integrin].
pubmed:affiliation
Department of Orthopaedic Surgery, Yugawara kosei-nenkin Hosipital.
pubmed:publicationType
Journal Article, English Abstract