Source:http://linkedlifedata.com/resource/pubmed/id/15775345
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2005-3-18
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pubmed:abstractText |
Osteoclasts are terminally differentiated multinucleated cells which play important roles in not only physiological but also pathophysiological bone resorption. Osteoclastic bone resorption can be divided into several processes; 1) Proliferation of osteoclast precursors on bone surfaces; 2) Differentiation of the precursors into mononuclear osteoclasts; 3) Multinucleation; 4) Adhesion to bone surfaces and cytoskeletal organization (activation); 5) Expanding resorption lacunae by cell migration; 6) Apoptosis. alphavbeta3 integrins, heterodimeric adhesion receptors, are involved in these steps. In this chapter, we discuss this multifunctional molecule from the viewpoint of osteoclasts.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:status |
PubMed-not-MEDLINE
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pubmed:month |
May
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pubmed:issn |
0917-5857
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
607-14
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pubmed:dateRevised |
2006-11-15
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pubmed:year |
2002
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pubmed:articleTitle |
[Osteoclasts and alphavbeta3 integrin].
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pubmed:affiliation |
Department of Orthopaedic Surgery, Yugawara kosei-nenkin Hosipital.
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pubmed:publicationType |
Journal Article,
English Abstract
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