Linked Life Data

15773609

Source:http://linkedlifedata.com/resource/pubmed/id/15773609

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-3-18
pubmed:abstractText
Amblyopia, a major cause of vision loss, is a developmental disorder of visual perception commonly associated with strabismus (squint). Although defined by a reduction in visual acuity, severe distortions of perceived visual location are common in strabismic amblyopia. These distortions can help us understand the cortical coding of visual location and its development in normal vision, as well as in amblyopia. The history of retinotopic mapping in the visual cortex highlights the potential impact of amblyopia. Theories of amblyopia include topological disarray of receptors in primary visual cortex, undersampling from the amblyopic eye compared with normal eyes, and the presence of anomalous retinal correspondence or multiple cortical representations of the strabismic fovea. We examined the distortions in a strabismic amblyope, using a pop-out localization task, in which normal observers made errors dependent on the visual context of the stimulus. The localization errors of the strabismic amblyope were abnormal. We found that none of the available theories could fully explain this one patient's localization performance. Instead, the observed behavior suggests that multiple adaptations of the underlying cortical topology are possible simultaneously in different parts of the visual field.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0301-0066
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-107
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Location coding by the human visual system: multiple topological adaptations in a case of strabismic amblyopia.
pubmed:affiliation
School of Optometry, University of California at Berkeley, Berkeley, CA 94720-2020, USA. ariellap@berkeley.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, N.I.H., Extramural