Linked Life Data

15772372

Source:http://linkedlifedata.com/resource/pubmed/id/15772372

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2005-11-14
pubmed:abstractText
The large-scale neural dynamics underlying higher cognitive processes are characterized by at least three types of stimulus-response: (i) the resetting of ongoing oscillatory brain activity without concomitant changes in response amplitude (phase alignment response); (ii) the addition of response amplitude to the ongoing brain activity in a time-locked manner (evoked response); and (iii) the addition of response amplitude that is not time-locked (induced response). Recent animal studies identified evoked responses as a characteristic neural response during stimulus perception but leave open the possibility that higher cognition, such as memory, is characterized more predominantly by phase alignment and/or induced responses. Using whole-head single-trial magnetoencephalography data from eight healthy adults, we show that all three types of response are related to the discrimination of old and new stimuli in a visual word recognition memory paradigm. In four subjects, single-trial evoked responses were the single constituents of event-related field old/new differences that have been previously related to familiarity-based and recollection-based recognition memory. While these data show that the oscillatory brain dynamics underlying recognition memory are characterized by a complex mix of three types of stimulus-response, they also clearly implicate evoked responses in higher cognitive processes such as recognition memory.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1047-3211
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1992-2002
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
The oscillatory dynamics of recognition memory and its relationship to event-related responses.
pubmed:affiliation
Department of Neurology II, Otto von Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany. emrah.duezel@medizin.uni-magdeburg.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't