Linked Life Data

15765978

Source:http://linkedlifedata.com/resource/pubmed/id/15765978

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-3-15
pubmed:abstractText
Hepatocyte growth factor (HGF) also known as "scatter factor" (SF), was identified for the first time as a potent mitogen of primary cultured hepatocytes; it has multiple biological responses in a variety of cells including mitogenic, motogenic, morphogenic and antiapoptotic activities. It is secreted as an inactive single chain protein and isproteolitically cleaved to form an active two chain HGF. The hepatocyte growth factor activator (HGFA) is the principal activator of HGF. HGF exerts its biological effects through transmembrane tyrosine kinase receptor (c-Met). HGF is a growth factor displaying a remarkable ability to promote tissue repair and organ regeneration after injury. Therefore attention should be set on the clinical potential of HGF as a treatment for various diseases.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0375-0906
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-50
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:articleTitle
[Hepatocyte growth factor (HGF) and its therapeutic applications].
pubmed:affiliation
Instituto de Biología Molecular y Terapia Génica, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Guadalajara, Jalisco.
pubmed:publicationType
Journal Article, English Abstract, Review