Linked Life Data

15764084

Source:http://linkedlifedata.com/resource/pubmed/id/15764084

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2005-3-14
pubmed:abstractText
Excessive activation of poly(ADP-ribose) polymerase (PARP), a nuclear enzyme that is activated by DNA damage, leads to neuronal cell death through depletion of ATP. The purpose of this study was to determine whether inhibition of PARP has some neuroprotective effects on the N-methyl-D-aspartate (NMDA)-induced functional and morphological injury to the rabbit retina.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0271-3683
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
403-11
pubmed:meshHeading
pubmed-meshheading:15764084-Animals, pubmed-meshheading:15764084-Benzamides, pubmed-meshheading:15764084-Cell Count, pubmed-meshheading:15764084-Cytoprotection, pubmed-meshheading:15764084-Dizocilpine Maleate, pubmed-meshheading:15764084-Dose-Response Relationship, Drug, pubmed-meshheading:15764084-Electroretinography, pubmed-meshheading:15764084-Enzyme Activation, pubmed-meshheading:15764084-Enzyme Inhibitors, pubmed-meshheading:15764084-Evoked Potentials, Visual, pubmed-meshheading:15764084-Excitatory Amino Acid Agonists, pubmed-meshheading:15764084-Excitatory Amino Acid Antagonists, pubmed-meshheading:15764084-Immunoenzyme Techniques, pubmed-meshheading:15764084-Injections, pubmed-meshheading:15764084-N-Methylaspartate, pubmed-meshheading:15764084-Poly(ADP-ribose) Polymerases, pubmed-meshheading:15764084-Rabbits, pubmed-meshheading:15764084-Retina, pubmed-meshheading:15764084-Retinal Diseases, pubmed-meshheading:15764084-Retinal Ganglion Cells, pubmed-meshheading:15764084-Vitreous Body
pubmed:year
2004
pubmed:articleTitle
Effects of poly(ADP-ribose) polymerase inhibitor on NMDA-induced retinal injury.
pubmed:affiliation
Department of Ophthalmology, Osaka Medical College, Osaka, Japan. hidehirooku@aol.com
pubmed:publicationType
Journal Article