| pubmed-article:15763978 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15763978 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:15763978 | lifeskim:mentions | umls-concept:C0012634 | lld:lifeskim |
| pubmed-article:15763978 | lifeskim:mentions | umls-concept:C1550594 | lld:lifeskim |
| pubmed-article:15763978 | lifeskim:mentions | umls-concept:C0752095 | lld:lifeskim |
| pubmed-article:15763978 | lifeskim:mentions | umls-concept:C1548760 | lld:lifeskim |
| pubmed-article:15763978 | lifeskim:mentions | umls-concept:C1547300 | lld:lifeskim |
| pubmed-article:15763978 | lifeskim:mentions | umls-concept:C0580822 | lld:lifeskim |
| pubmed-article:15763978 | lifeskim:mentions | umls-concept:C1513387 | lld:lifeskim |
| pubmed-article:15763978 | pubmed:issue | 5-6 | lld:pubmed |
| pubmed-article:15763978 | pubmed:dateCreated | 2005-3-14 | lld:pubmed |
| pubmed-article:15763978 | pubmed:abstractText | We tested a set of commercially available probes to determine the feasibility and accuracy of FISH in the detection of abnormalities in 13 patients with Chronic Lymphocytic Leukemia (CLL) with a particular aggressive clinical disease. We utilized three different probes for the 13q12-14 region, one for the centromeric region of chromosome 12, one for the P53 gene at 17p13.1 and one for 3'-5' IGH at 14q32, covering the entire region of IGH, thus potentially allowing to detect more rearrangements. Conventional cytogenetic study showed a normal karyotype in 8/13 patients. FISH was able to detect chromosomal abnormalities in 10/13 pts (85%): +12 in 4 pts (38%); del 13q in 4 (38%); del 17p in 3 (35%); del of 5'-IGH in 1 (15%). In conclusion FISH confirmed its ability to improve the detection of cytogenetic abnormalities especially in patients with an aggressive disease. | lld:pubmed |
| pubmed-article:15763978 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15763978 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15763978 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15763978 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15763978 | pubmed:issn | 1024-5332 | lld:pubmed |
| pubmed-article:15763978 | pubmed:author | pubmed-author:LauriaFrances... | lld:pubmed |
| pubmed-article:15763978 | pubmed:author | pubmed-author:ForconiFrance... | lld:pubmed |
| pubmed-article:15763978 | pubmed:author | pubmed-author:GozzettiAless... | lld:pubmed |
| pubmed-article:15763978 | pubmed:author | pubmed-author:RaspadoriDona... | lld:pubmed |
| pubmed-article:15763978 | pubmed:author | pubmed-author:TozzuoliDanie... | lld:pubmed |
| pubmed-article:15763978 | pubmed:author | pubmed-author:CrupiRosariaR | lld:pubmed |
| pubmed-article:15763978 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15763978 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:15763978 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15763978 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15763978 | pubmed:pagination | 383-5 | lld:pubmed |
| pubmed-article:15763978 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:meshHeading | pubmed-meshheading:15763978... | lld:pubmed |
| pubmed-article:15763978 | pubmed:articleTitle | Molecular cytogenetic analysis of B-CLL patients with aggressive disease. | lld:pubmed |
| pubmed-article:15763978 | pubmed:affiliation | Department of Medicine and Immunological Sciences, Division of Hematology and Transplants, University of Siena, Siena, Italy. gozzetti.unisi.it | lld:pubmed |
| pubmed-article:15763978 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15763978 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15763978 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15763978 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15763978 | lld:pubmed |
