Linked Life Data

15763172

Source:http://linkedlifedata.com/resource/pubmed/id/15763172

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-3-14
pubmed:abstractText
Abnormalities in motor cortical excitation and inhibition have been reported in patients with writer's cramp, at rest and during muscle activation. We were interested in whether such abnormalities might be task-specific and depended on the type of movement task used to activate the dystonic hand. We therefore assessed motor-evoked potentials (facilitation/rest MEP amplitude ratio) and duration of the cortical silent period (CSP) from the right first dorsal interosseus (FDI) muscle to transcranial magnetic stimulation (TMS) in 10 patients with writer's cramp and in 10 healthy volunteers performing pincer and power gripping tasks. The mean facilitation/rest MEP amplitude ratio measured during the pincer grip task was significantly larger in dystonic subjects than in controls, but in the power grip condition was similar in the two groups. The CSP measured in the power grip condition was of similar length in normal controls and dystonic subjects, but in the pincer grip condition was significantly shorter in patients than in controls. These results indicate a task-specific impairment of motor cortical excitation and inhibition in writer's cramp.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
11
pubmed:volume
378
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Task-specific impairment of motor cortical excitation and inhibition in patients with writer's cramp.
pubmed:affiliation
Unità Operativa di Neurologia, Ospedale Civile Borgo Trento, Piazzale Stefani 1, 37100 Verona, Italy. micheletinazzi@libero.it
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't