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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-3-14
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pubmed:abstractText |
Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver-related morbidity and is frequently associated with obesity and metabolic syndrome. The recently discovered hormone adiponectin is produced by adipose tissue, and low plasma adiponectin is considered a key factor in the development of the insulin resistance underlying metabolic syndrome. Animal studies suggest that adiponectin may protect against non-alcoholic steatohepatitis, but direct evidence in humans is lacking. We therefore conducted this study to assess the relationship between plasma adiponectin and nonalcoholic fatty liver disease to explore its role in the pathogenesis of this disease.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adiponectin,
http://linkedlifedata.com/resource/pubmed/chemical/Alanine Transaminase,
http://linkedlifedata.com/resource/pubmed/chemical/Alkaline Phosphatase,
http://linkedlifedata.com/resource/pubmed/chemical/Aspartate Aminotransferases,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/Leptin,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides,
http://linkedlifedata.com/resource/pubmed/chemical/gamma-Glutamyltransferase
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0804-4643
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
152
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-8
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15762194-Adiponectin,
pubmed-meshheading:15762194-Adult,
pubmed-meshheading:15762194-Alanine Transaminase,
pubmed-meshheading:15762194-Alkaline Phosphatase,
pubmed-meshheading:15762194-Aspartate Aminotransferases,
pubmed-meshheading:15762194-Blood Glucose,
pubmed-meshheading:15762194-Cholesterol, HDL,
pubmed-meshheading:15762194-Fatty Liver,
pubmed-meshheading:15762194-Female,
pubmed-meshheading:15762194-Humans,
pubmed-meshheading:15762194-Insulin,
pubmed-meshheading:15762194-Insulin Resistance,
pubmed-meshheading:15762194-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:15762194-Leptin,
pubmed-meshheading:15762194-Male,
pubmed-meshheading:15762194-Multivariate Analysis,
pubmed-meshheading:15762194-Regression Analysis,
pubmed-meshheading:15762194-Triglycerides,
pubmed-meshheading:15762194-gamma-Glutamyltransferase
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pubmed:year |
2005
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pubmed:articleTitle |
Plasma adiponectin is decreased in nonalcoholic fatty liver disease.
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pubmed:affiliation |
Endocrine-Metabolic Laboratory, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy. claudio.pagano@unipd.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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