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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-3-24
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pubmed:abstractText |
Stimulation of Dictyostelium discoideum with cAMP evokes an elevation of the cytosolic free Ca2+ concentration ([Ca2+]i). The [Ca2+]i-change is composed of liberation of stored Ca2+ and extracellular Ca2+-entry. The significance of the [Ca2+]i-transient for chemotaxis is under debate. Abolition of chemotactic orientation and migration by Ca2+-buffers in the cytosol indicates that a [Ca2+]i-increase is required for chemotaxis. Yet, the iplA- mutant disrupted in a gene bearing similarity to IP3-receptors of higher eukaryotes aggregates despite the absence of a cAMP-induced [Ca2+]i-transient which favours the view that [Ca2+]i-changes are insignificant for chemotaxis.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-10722673,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-10821794,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-10970875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-12135922,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-12456728,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-14973132,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-15561583,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-16948639,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-17557409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-2191567,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-2505254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-3838314,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-6323484,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-7736566,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-7982261,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-7983172,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-8227052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-8573107,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-8895562,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-8937985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-9232353,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-9354808,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-9355757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-9427292,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-9601085,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15760480-9781694
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2121
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
13
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
2005
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pubmed:articleTitle |
Ca2+ regulation in the absence of the iplA gene product in Dictyostelium discoideum.
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pubmed:affiliation |
Department of Chemistry and Biochemistry, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0601, USA. rschalos@chem.ucsd.edu <rschalos@chem.ucsd.edu>
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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