|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2005-3-8
|
|
pubmed:abstractText |
The authors studied the tolerability of subcutaneous interferon beta-1a (IFNbeta-1a) in 51 patients with early-onset multiple sclerosis. The most frequent systemic adverse effects were flu-like symptoms in 65%. Laboratory abnormalities included asymptomatic leukopenia (27%) and elevated hepatic transaminases (35%). Treatment with IFNbeta-1a was safe and well tolerated in the majority of children and adolescents.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1526-632X
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
8
|
|
pubmed:volume |
64
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
888-90
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15753430-Adjuvants, Immunologic,
pubmed-meshheading:15753430-Adolescent,
pubmed-meshheading:15753430-Age of Onset,
pubmed-meshheading:15753430-Central Nervous System,
pubmed-meshheading:15753430-Child,
pubmed-meshheading:15753430-Cohort Studies,
pubmed-meshheading:15753430-Dose-Response Relationship, Drug,
pubmed-meshheading:15753430-Female,
pubmed-meshheading:15753430-Humans,
pubmed-meshheading:15753430-Interferon-beta,
pubmed-meshheading:15753430-Leukopenia,
pubmed-meshheading:15753430-Liver,
pubmed-meshheading:15753430-Male,
pubmed-meshheading:15753430-Multiple Sclerosis, Relapsing-Remitting,
pubmed-meshheading:15753430-Recurrence,
pubmed-meshheading:15753430-Retrospective Studies,
pubmed-meshheading:15753430-Transaminases,
pubmed-meshheading:15753430-Treatment Outcome
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Treatment of early onset multiple sclerosis with subcutaneous interferon beta-1a.
|
|
pubmed:affiliation |
Department of Pediatrics and Pediatric Neurology, Georg-August-University Goettingen, Robert-Koch-Strasse 40, 37075 Germany. E-mail: dpohl@med.uni-goettingen.de.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
