Linked Life Data

15752841

Source:http://linkedlifedata.com/resource/pubmed/id/15752841

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
19
pubmed:dateCreated
2005-3-8
pubmed:abstractText
Recombinant vaccines containing Ii sequences were employed to elicit an antibody response. Gene gun immunisation of mice with the recombinant Ii-antigen-encoding vectors induced antigen-specific antibodies. Antibody levels were substantially elevated when the DNA construct was extended by a sequence encoding the protease inhibitory domain of the invariant chain isoform Ii41. Employing this approach, we raised antibodies specific for a novel MHC class III encoded protein. The antibodies identify the 216 kDa BAT2 polypeptide. Immunostaining of embryonic tissue sections showed specific expression, especially in central nervous tissue, and suggests BAT2 as a novel differentiation marker.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0264-410X
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2540-50
pubmed:dateRevised
2011-9-28
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Antibodies generated by a novel DNA vaccination identify the MHC class III encoded BAT2 polypeptide.
pubmed:affiliation
Division of Immunobiology, Institute of Molecular Physiology, University of Bonn, Römerstrasse 164, 53117 Bonn, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't