rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2005-4-13
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pubmed:abstractText |
The overexpression of HER-2 occurs in a minority of patients with nonsmall cell lung carcinoma. Trastuzumab, which is a monoclonal antibody to HER-2, is an effective treatment in some women with breast carcinomas that overexpress HER-2, as demonstrated by immunohistochemistry. The objective of this Phase II study was to determine whether trastuzumab would effect responses in patients with nonsmall cell lung carcinoma who had tumors that overexpressed HER-2.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/CA03927,
http://linkedlifedata.com/resource/pubmed/grant/CA04326,
http://linkedlifedata.com/resource/pubmed/grant/CA08025,
http://linkedlifedata.com/resource/pubmed/grant/CA11028,
http://linkedlifedata.com/resource/pubmed/grant/CA21060,
http://linkedlifedata.com/resource/pubmed/grant/CA31946,
http://linkedlifedata.com/resource/pubmed/grant/CA336,
http://linkedlifedata.com/resource/pubmed/grant/CA33601,
http://linkedlifedata.com/resource/pubmed/grant/CA45418,
http://linkedlifedata.com/resource/pubmed/grant/CA45808,
http://linkedlifedata.com/resource/pubmed/grant/CA47577,
http://linkedlifedata.com/resource/pubmed/grant/CA47642,
http://linkedlifedata.com/resource/pubmed/grant/CA77440
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0008-543X
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pubmed:author |
|
pubmed:copyrightInfo |
(c) 2005 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1670-5
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15751020-Adult,
pubmed-meshheading:15751020-Aged,
pubmed-meshheading:15751020-Aged, 80 and over,
pubmed-meshheading:15751020-Antibodies, Monoclonal,
pubmed-meshheading:15751020-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:15751020-Antineoplastic Agents,
pubmed-meshheading:15751020-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:15751020-Female,
pubmed-meshheading:15751020-Humans,
pubmed-meshheading:15751020-Lung Neoplasms,
pubmed-meshheading:15751020-Male,
pubmed-meshheading:15751020-Middle Aged,
pubmed-meshheading:15751020-Receptor, erbB-2,
pubmed-meshheading:15751020-Survival Rate,
pubmed-meshheading:15751020-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
Lack of trastuzumab activity in nonsmall cell lung carcinoma with overexpression of erb-B2: 39810: a phase II trial of Cancer and Leukemia Group B.
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pubmed:affiliation |
Department of Internal Medicine, University of Iowa, Iowa City, Iowa 52242-1099, USA. gerald-clamon@uiowa.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II
|