Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1992-5-29
|
pubmed:abstractText |
Eosinophilic granular bodies (EGBs) are studied immunocytochemically and ultrastructurally in a case of low-grade and a case of high-grade astrocytoma. EGBs are recognized as brightly eosinophilic round bodies of variable size in hematoxylin and eosin-stained sections. Immunocytochemically some EGBs are positive for antibodies raised against alpha B-crystallin, ubiquitin and glial fibrillary acidic protein with the staining patterns for each being different from one another. Ultrastructurally EGBs consist of membrane-bound round body of various diameter ranging from 50 nm to 20 microns. Small EGBs contain electron-dense homogeneous material with occasional myelin figures, while electron-dense homogeneous material or loose granular profiles. Our studies demonstrate (1) ultrastructural variety of EGB; (2) and alpha B-crystallin epitope in EGB; and (3) the presence of EGB in high-grade as well as low-grade astrocytoma.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-6322
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
83
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
408-14
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:1575017-Adult,
pubmed-meshheading:1575017-Antibodies,
pubmed-meshheading:1575017-Antibodies, Monoclonal,
pubmed-meshheading:1575017-Astrocytoma,
pubmed-meshheading:1575017-Brain Neoplasms,
pubmed-meshheading:1575017-Child,
pubmed-meshheading:1575017-Crystallins,
pubmed-meshheading:1575017-Cytoplasmic Granules,
pubmed-meshheading:1575017-Eosinophils,
pubmed-meshheading:1575017-Glial Fibrillary Acidic Protein,
pubmed-meshheading:1575017-Humans,
pubmed-meshheading:1575017-Immunohistochemistry,
pubmed-meshheading:1575017-Intermediate Filaments,
pubmed-meshheading:1575017-Male,
pubmed-meshheading:1575017-Microscopy, Electron
|
pubmed:year |
1992
|
pubmed:articleTitle |
Immunocytochemical and ultrastructural studies of eosinophilic granular bodies in astrocytic tumors.
|
pubmed:affiliation |
Department of Pathology, University of North Carolina, Chapel Hill 27599-7525.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
|