rdf:type |
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0022116,
umls-concept:C0086597,
umls-concept:C0155626,
umls-concept:C0185117,
umls-concept:C0205087,
umls-concept:C0205263,
umls-concept:C0242184,
umls-concept:C0871261,
umls-concept:C1522564,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911684,
umls-concept:C2911692
|
pubmed:issue |
2
|
pubmed:dateCreated |
2005-3-7
|
pubmed:abstractText |
We report hypoxia-inducible factor-1 (HIF-1) expression in myocardium of patients with recent acute myocardial infarction (AMI), supporting the hypothesis of HIF-1 as a possible mediator of response to ischemia. A potential diagnostic role of determining tissue expression of HIF-1 as a marker of ischemia, and potential therapeutic implications by trying to modulate HIF-1 activity in order to promote beneficial effects of HIF-1 related genes (e.g. expression of vascular endothelial growth factor (VEGF)) may derive.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0167-5273
|
pubmed:author |
pubmed-author:AbbateAntonioA,
pubmed-author:BaldiAlfonsoA,
pubmed-author:BiasucciLuigi MLM,
pubmed-author:Biondi-ZoccaiGiuseppe G LGG,
pubmed-author:BussaniRossanaR,
pubmed-author:LeoneAntonio MariaAM,
pubmed-author:ParisiQuintinoQ,
pubmed-author:PetroliniAlessandroA,
pubmed-author:SantiniDanieleD,
pubmed-author:ScarpaSusannaS,
pubmed-author:SilvestriFurioF,
pubmed-author:VasaturoFortunataF
|
pubmed:issnType |
Print
|
pubmed:day |
18
|
pubmed:volume |
99
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
337-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15749199-Aged,
pubmed-meshheading:15749199-Animals,
pubmed-meshheading:15749199-Cadaver,
pubmed-meshheading:15749199-DNA-Binding Proteins,
pubmed-meshheading:15749199-Disease Models, Animal,
pubmed-meshheading:15749199-Female,
pubmed-meshheading:15749199-Gene Expression,
pubmed-meshheading:15749199-Humans,
pubmed-meshheading:15749199-Hypoxia-Inducible Factor 1,
pubmed-meshheading:15749199-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:15749199-Male,
pubmed-meshheading:15749199-Myocardial Infarction,
pubmed-meshheading:15749199-Myocardium,
pubmed-meshheading:15749199-Myocytes, Cardiac,
pubmed-meshheading:15749199-Nuclear Proteins,
pubmed-meshheading:15749199-Rats,
pubmed-meshheading:15749199-Rats, Sprague-Dawley,
pubmed-meshheading:15749199-Time Factors,
pubmed-meshheading:15749199-Transcription Factors
|
pubmed:year |
2005
|
pubmed:articleTitle |
Hypoxia inducible factor-1 expression mediates myocardial response to ischemia late after acute myocardial infarction.
|
pubmed:publicationType |
Letter,
Comparative Study
|